Endometriosis As a Cause of Infertility

Endometriosis is one of the highest recorded conditions related to infertility. About 75% of total infertile cases are caused by biological make-up problems, including utero formation and pelvic conditions.

About 30% to 40% of the women suffering from Endrometriosis are also reported to be infertile. Though the relation of endometriosis and infertility is yet to be established, the presence of masses of tissues and scarrings in the pelvic and utero area brought on by the conditions is one of the many causes of infertility.

Endometriosis is defined as the condition wherein Endometrium tissue grows and lines not only the uterine linings, but also organs like intestines, pelvis, vaginal walls, fallopian tubes, etc. These deposits in unlikely areas cause menstruation to backflow onto the fallopian tubes and cause scarrings along the way. These abrasions have been pointed to play a role in infertility.

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The Top 100 Traditional Remedies: 100 Home Remedies for Health and Well-Being

Product Description
Grandma knew best! These 100 tried-and-true treatments for the most common ailments were staples in her home. With the growth of pharmaceuticals, many of them were temporarily eclipsed—but the newest scientific research proves that many of these healthy foods and herbs are well worth rediscovering. It’s easy to find what you need: the guide is broken up into illustrated chapters on fruits, vegetables, legumes and beans, nuts and seeds, whole grains, herbs, spice… More >>

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In this study, a team led by Gosse J. Adema, Ph.D., of the Department of Tumor Immunology, at the Radboud University Nijmegen Medical Centre, the Netherlands, and colleagues assessed the role of DC-SCRIPT as a co-regulator of nuclear receptors, including estrogen receptor (ER), progesterone receptor (PR)-B, peroxisome proliferator-activated receptor gamma, and retinoic acid receptor alpha. Prognostic value was assessed in three independent cohorts of breast cancer patients.

The researchers found that DC-SCRIPT suppressed ER- and PR-mediated transcription in a ligand-dependent fashion, whereas it enhanced the activity of the other two receptors. Quantification of DC-SCRIPT mRNA expression in the three cohorts of patients revealed that this expression is an independent prognostic factor for breast cancer patients with ER- and/or PR-positive tumors, according to the authors.

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