Gene linked to kidney cancer in children discovered
Cancer Research UK-funded scientists have identified two genes linked to Wilms’ tumour – a type of childhood kidney cancer – according to research published in Clinical Cancer Research.
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This finding by a team of biologists at Boston University is the first to link choline consumption during pregnancy to breast cancer. It also is the first to identify possible choline-related genetic changes that affect breast cancer survival rates.
“We’ve known for a long time that some agents taken by pregnant women, such as diethylstibesterol, have adverse consequences for their daughters,” said Gerald Weissmann, M.D., Editor-in-Chief of The FASEB Journal. “But there’s an upside. The emerging science of epigenetics has yielded a breakthrough. For the first time, we’ve learned that we might be able to prevent breast cancer as early as a mother’s pregnancy.”
» Read more: Eating Eggs When Pregnant Affects Breast Cancer In Offspring Terramed Alliance News
Ze-Guang Han and colleagues, at the Chinese National Human Genome Center at Shanghai, People’s Republic of China, have now identified SCARA5 as a candidate tumor suppressor gene in human hepatocellular carcinoma (HCC), a form of liver cancer that is the fifth most common cancer worldwide.
The research is reported in the Journal of Clinical Investigation.
» Read more: New Suppressor of Common Liver Cancer