Lung Cancer – Causes, Symptoms and Treatment

Lung cancer is the malignant transformation and expansion of lung tissue, and is the most lethal of all cancers worldwide, responsible for 1.2 million deaths annually. It is a leading cause of cancer death in men and women in the United States. Cigarette smoking causes most lung cancers. The more cigarettes you smoke per day and the earlier you started smoking, the greater your risk of lung cancer. High levels of pollution, radiation and asbestos exposure may also increase risk. There are many types of lung cancer. Each type of lung cancer grows and spreads in different ways and is treated differently. Treatment also depends on the stage, or how advanced it is.

Treatment may include chemotherapy, radiation and surgery. Lung cancer that originates in the cells of the lungs is called primary lung cancer; however, cancer may also spread to the lung from other parts of the body. Metastatic cancers spread to the lungs most commonly from the breast, colon, prostate, kidney, thyroid gland, stomach, cervix, rectum, testis, bone, and skin (melanoma). More than 90% of primary lung cancers start in the bronchi such lung cancer is called bronchogenic carcinoma. The specific types of lung cancer are small cell carcinoma, squamous cell carcinoma, large cell carcinoma, and adenocarcinoma. The last three types of lung cancer are often referred to as nonsmall cell lung cancers. Alveolar cell carcinoma originates in the small air sacs of the lung (alveoli). Although alveolar cell carcinoma can occur at a single site, it often develops simultaneously in more than one area of the lung. Less common lung tumors are bronchial carcinoid (which may be cancerous or noncancerous), chondromatous hamartoma and sarcoma. Lymphoma is a cancer of the lymphatic system; it may start in the lungs or spread to them.

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FDA Approved Leukemia Drugs Shows Promise In Ovarian Cancer Cells

The drug, when paired with a chemotherapy regimen, was even more effective in fighting ovarian cancer in cell lines in which signaling of the Src family kinases, associated with the deadly disease, is activated.

The study appears in the Nov. 10, 2009 edition of the British Medical Journal.

Ovarian cancer, which will strike 21,600 women this year and kill 15,500, causes more deaths than any other cancer of the female reproductive system. Few effective therapies for ovarian cancer exist, so it would be advantageous for patients if a new drug could be found that fights the cancer, said Gottfried Konecny, an assistant professor of hematology/oncology, a Jonsson Cancer Center researcher and first author of the study.

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