Most Still Not Getting Screened For Skin Cancer
Despite all of the constant warnings about the dangers of sun exposure, skin cancer cases continue to rise with more than 3.5 million new cases diagnosed every year.
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Most Still Not Getting Screened For Skin Cancer
Breast Cancer: Women’s Killer
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The book identifies treatment strategies that prolong patient s life and improve chances of survival through non-aggressive clinical forms. The author believes that breast cancer is determined by an unknown virus…. More >>
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DC-SCRIPT Found to Have Prognostic Value in Breast Cancer
In this study, a team led by Gosse J. Adema, Ph.D., of the Department of Tumor Immunology, at the Radboud University Nijmegen Medical Centre, the Netherlands, and colleagues assessed the role of DC-SCRIPT as a co-regulator of nuclear receptors, including estrogen receptor (ER), progesterone receptor (PR)-B, peroxisome proliferator-activated receptor gamma, and retinoic acid receptor alpha. Prognostic value was assessed in three independent cohorts of breast cancer patients.
The researchers found that DC-SCRIPT suppressed ER- and PR-mediated transcription in a ligand-dependent fashion, whereas it enhanced the activity of the other two receptors. Quantification of DC-SCRIPT mRNA expression in the three cohorts of patients revealed that this expression is an independent prognostic factor for breast cancer patients with ER- and/or PR-positive tumors, according to the authors.
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