Terramed Alliance News Healthy Diet Can’t Hurt, May Help Breast Cancer Patients

Breast cancer is the second leading cause of cancer death in women in the United States, with approximately 180,000 cases diagnosed each year. Researchers continue to evaluate environmental factors, such as diet, that influence the development of breast cancer. Numerous studies have provided a wealth of often-contradictory information about the detrimental and protective factors of different foods. High fruit and vegetable consumption has been associated with a reduced risk for developing at least 10 different cancers. Studies evaluating the influence of diet on breast cancer prognosis have produced inconsistent results.

Researchers from California and Utah assessed a cohort of 1,901 women from the Life After Cancer Epidemiology (LACE) Study who were diagnosed with early-stage breast cancer between 1997 and 2000. Upon entering the study, the women completed a food frequency questionnaire (FFQ). The researchers used the data from the FFQs to identify two dietary patterns among the women: a prudent diet included high intakes of fruits, vegetables, whole grains, and poultry, whereas a Western diet included high intakes of red and processed meats and refined grains. The researchers then evaluated the rates of recurrence, overall death, death from breast cancer, and death from causes other than breast cancer. As of May 2008, there were 268 breast cancer recurrences and 226 deaths, 128 of which were attributed to breast cancer.

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An Article on Cancer

AN ARTICLE ON CANCER

What is cancer?

Cancer is the general term used for diseases in which normal cells separate without any control thus involving other tissues. Cancer cells can also spread to various parts of the body through the blood and lymph system.

 

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Pancreatic Tumors Are Marked for Immunotherapy

The marker is mesothelin, a protein normally found on mesothelial cells that line the body cavities. Several types of cancer cells make large amounts of mesothelin, which then circulates in the blood.

Mesothelin levels in the blood were shown in earlier studies to predict survival in patients with ovarian cancer and mesothelioma (a cancer of mesothelial cells). The researchers wanted to know if elevated blood levels of mesothelin could be used as a biological indicator for pancreatic disease. The study, published this month in Clinical Cancer Research, also examined whether the protein could be useful for immune-based cancer treatments.

“All pancreatic tumor specimens we tested displayed mesothelin on them, and the protein could be detected in the blood of 99 percent of our study patients with pancreatic cancer,” says co-senior author Peter Goedegebuure, Ph.D., research associate professor of surgery. “Other studies suggest that mesothelin plays an essential role in the development and growth of cancer, making it an ideal target for therapy.”

» Read more: Pancreatic Tumors Are Marked for Immunotherapy

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