Breast cancer should be a major concern for all women today since it is the single most common type of cancer in women. There is about a 15% chance of developing breast cancer by the age of 90 if you are a woman and have a full, healthy lifestyle. This percentage may not sound like a lot, but it is one of the highest as far as cancer risks go. You can lower this risk by having a breast cancer test frequently.
Have a Basic Mammogram Regularly
» Read more: Breast Cancer in Women – Know the Facts
In this study, a team led by Gosse J. Adema, Ph.D., of the Department of Tumor Immunology, at the Radboud University Nijmegen Medical Centre, the Netherlands, and colleagues assessed the role of DC-SCRIPT as a co-regulator of nuclear receptors, including estrogen receptor (ER), progesterone receptor (PR)-B, peroxisome proliferator-activated receptor gamma, and retinoic acid receptor alpha. Prognostic value was assessed in three independent cohorts of breast cancer patients.
The researchers found that DC-SCRIPT suppressed ER- and PR-mediated transcription in a ligand-dependent fashion, whereas it enhanced the activity of the other two receptors. Quantification of DC-SCRIPT mRNA expression in the three cohorts of patients revealed that this expression is an independent prognostic factor for breast cancer patients with ER- and/or PR-positive tumors, according to the authors.
» Read more: DC-SCRIPT Found to Have Prognostic Value in Breast Cancer
Fruits, Vegetables Offer Little Cancer Protection
Eating a diet rich in fruits and vegetables is good for many reasons, but don’t expect it to offer much protection against cancer, according to a new study.
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