Winning the war on cancer? Disease rates in U.S. drop below where they were in 1970s
It’s too soon to declare a victory, but it appears that the U.S. may be winning the battle with cancer.
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Winning the war on cancer? Disease rates in U.S. drop below where they were in 1970s
DC-SCRIPT Found to Have Prognostic Value in Breast Cancer
In this study, a team led by Gosse J. Adema, Ph.D., of the Department of Tumor Immunology, at the Radboud University Nijmegen Medical Centre, the Netherlands, and colleagues assessed the role of DC-SCRIPT as a co-regulator of nuclear receptors, including estrogen receptor (ER), progesterone receptor (PR)-B, peroxisome proliferator-activated receptor gamma, and retinoic acid receptor alpha. Prognostic value was assessed in three independent cohorts of breast cancer patients.
The researchers found that DC-SCRIPT suppressed ER- and PR-mediated transcription in a ligand-dependent fashion, whereas it enhanced the activity of the other two receptors. Quantification of DC-SCRIPT mRNA expression in the three cohorts of patients revealed that this expression is an independent prognostic factor for breast cancer patients with ER- and/or PR-positive tumors, according to the authors.
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How to Prevent Cancer with Proper Diet and Supplements
By epidemiological studies and by direct trials, much evidence has by now been gathered about the cancer prevention effects of certain diet measures, of specific food sources and of specific supplements of natural substances.
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» Read more: How to Prevent Cancer with Proper Diet and Supplements