BioSante plans new prostate cancer drug testing
BioSante Pharmaceuticals Inc. said Monday it hopes to restart testing of an experimental prostate cancer drug almost two years after the research was stopped.
Read more on AP via Yahoo! Finance
BioSante plans new prostate cancer drug testing
BioSante Pharmaceuticals Inc. said Monday it hopes to restart testing of an experimental prostate cancer drug almost two years after the research was stopped.
Read more on AP via Yahoo! Finance
In Pictures: The Arctic Monkeys For Teenage Cancer Trust
Did you see The Arctic Monkeys’ lead singer Alex Turner and with Jamie Cook performing at the Teenage Cancer Trust gig at the Royal Albert Hall, in west London? We did.
Read more on Anorak
In this study, a team led by Gosse J. Adema, Ph.D., of the Department of Tumor Immunology, at the Radboud University Nijmegen Medical Centre, the Netherlands, and colleagues assessed the role of DC-SCRIPT as a co-regulator of nuclear receptors, including estrogen receptor (ER), progesterone receptor (PR)-B, peroxisome proliferator-activated receptor gamma, and retinoic acid receptor alpha. Prognostic value was assessed in three independent cohorts of breast cancer patients.
The researchers found that DC-SCRIPT suppressed ER- and PR-mediated transcription in a ligand-dependent fashion, whereas it enhanced the activity of the other two receptors. Quantification of DC-SCRIPT mRNA expression in the three cohorts of patients revealed that this expression is an independent prognostic factor for breast cancer patients with ER- and/or PR-positive tumors, according to the authors.
» Read more: DC-SCRIPT Found to Have Prognostic Value in Breast Cancer