St. Charles County residents support cancer programs
Six cancer advocates from St. Charles County joined more than 123 American Cancer Society volunteers from across the state to share their stories with state lawmakers, while asking them to support legislation on cancer issues.
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In this study, a team led by Gosse J. Adema, Ph.D., of the Department of Tumor Immunology, at the Radboud University Nijmegen Medical Centre, the Netherlands, and colleagues assessed the role of DC-SCRIPT as a co-regulator of nuclear receptors, including estrogen receptor (ER), progesterone receptor (PR)-B, peroxisome proliferator-activated receptor gamma, and retinoic acid receptor alpha. Prognostic value was assessed in three independent cohorts of breast cancer patients.
The researchers found that DC-SCRIPT suppressed ER- and PR-mediated transcription in a ligand-dependent fashion, whereas it enhanced the activity of the other two receptors. Quantification of DC-SCRIPT mRNA expression in the three cohorts of patients revealed that this expression is an independent prognostic factor for breast cancer patients with ER- and/or PR-positive tumors, according to the authors.
» Read more: DC-SCRIPT Found to Have Prognostic Value in Breast Cancer
A man’s perspective of breast cancer
ANDREW Drummond has watched and supported his wife through the diagnosis and treatment of breast cancer on two occasions. At a McGrath Foundation and Grampians Integrated Cancer Service discussion evening tomorrow night for men whose partners have been affected by breast cancer, Mr Drummond will share what he has learnt.
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