PMH cancer researchers link ovarian hormone to breast stem cells growth

PMH cancer researchers link ovarian hormone to breast stem cells growth
( University Health Network ) Cancer researchers at Princess Margaret Hospital have discovered that the ovarian hormone progesterone plays a pivotal role in altering breast stem cells, a finding that has important implications for breast cancer risk.

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Eyelid Skin Cancer

Skin Cancer of the eyelids poses several diagnostic and management challenge. As a referral specialist, I see these patients well after a significant progression has occurred and the diagnosis is fairly obvious. The excision and reconstruction if these tumors requires a great degree of creativity and flexibility to achieve the optimal result.

The ultraviolet radiation that is primarily responsible for malignant transformation of skin cancer are 290 to 320 nm(UV-B). The most common malignancies affecting the periocular region are basal cell carcinoma, squamous cell carcinoma, sebaceous cell carcinoma, and malignant melanoma. Basal cell carcinoma accounts for 90% of all eyelid malignancies. The tumor primarily involves the lower eyelid (50% to 66%) and the medial canthus (25% to 30%). The upper eyelid is affected in 15% of cases and the lateral canthus in 5%. Although these statistics are helpful, many skin cancers involve adjacent anatomic areas such as the forehead and cheek, and pose even greater challenges in reconstruction.

» Read more: Eyelid Skin Cancer

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CTRC commences enrollment in Phase 2 trial of REOLYSIN combination for SCC lung cancer

CTRC commences enrollment in Phase 2 trial of REOLYSIN combination for SCC lung cancer
A virus that destroys cancer cells but leaves normal cells unharmed may offer hope to those affected by squamous cell carcinoma of the lungs (SCC lung cancer), according to investigators from the Cancer Therapy & Research Center (CTRC) at the University of Texas Health Science Center at San Antonio. The CTRC has started patient enrollment in a US Phase 2 clinical trial using intravenous …

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